404-808-7239


EPA and Sick Building



United States                                       Air and Radiation (6609J)                                     Research and Development

Environmental Protection                                                                                                  (MD-56) 
Agency                                                                                                                              February 1991    
Indoor Air Facts No. 4 (revised)
Sick Building Syndrome 




Introduction 
The term "sick building syndrome" (SBS) is used to  describe situations in which building occupants experience acute health and comfort effects that appear to be linked to time spent in a building, but no specific illness or cause can be identified. The complaints may be localized in a particular room or zone, or may be widespread throughout the building. In contrast, the term "building related illness" (BRI) is used when symptoms of diagnosable illness are identified and can be attributed directly to airborne building contaminants. A 1984 World Health Organization Committee report suggested that up to 30 percent of new and remodeled buildings worldwide may be the subject of excessive complaints related to indoor air quality (IAQ). Often this condition is temporary, but some buildings have long-term problems. Frequently,  problems result when a building is operated or maintained in a manner that is inconsistent with its original design or prescribed operating procedures.  Sometimes indoor air problems are a result of poor building design or occupant activities. Indicators of SBS include: • Building occupants complain of symptoms associated with acute discomfort, e.g., headache; eye, nose, or throat irritation; dry cough; dry or itchy skin; dizziness and nausea; difficulty in concentrating; fatigue; and sensitivity to odors.  • The cause of the symptoms is not known.  • Most of the complainants report relief soon after leaving the building.  Indicators of BRI include: • Building occupants complain of symptoms such as cough; chest tightness; fever, chills; and muscle aches. • The symptoms can be clinically defined and have clearly identifiable causes.  • Complainants may require prolonged recovery times after leaving the building.  It is important to note that complaints may result from other causes. These may include an illness contracted outside the building, acute sensitivity (e.g., allergies), job related stress or dissatisfaction, and other psychosocial factors. Nevertheless, studies show that symptoms may be caused or exacerbated by indoor air quality problems. 

Causes of Sick Building Syndrome 
The following have been cited causes of or contributing factors to sick building syndrome: Inadequate ventilation: In the early and mid 1900's, building ventilation standards called for approximately 15 cubic feet per minute (cfm) of outside air for each building occupant, primarily to dilute and remove body odors. As a result of the 1973 oil embargo, however, national energy conservation measures called for a reduction in the amount of outdoor air provided for ventilation to 5 cfm per occupant. In many cases these reduced outdoor air ventilation rates were found to beinadequate to maintain the health and comfort of building occupants. Inadequate ventilation, which may also occur if heating, ventilating, and air conditioning (HVAC) systems do not effectively distribute air to people in the building, is thought to be an important factor in SBS. In an effort to achieve acceptable IAQ while minimizing energy consumption, the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE) recently revised its ventilation standard to provide a minimum of 15 cfm of outdoor air per person (20 cfm/person in office spaces). Up to 60 cfm/person may be required in some spaces (such as smoking lounges) depending on the activities that normally occur in that space (see ASHRAE Standard 62-1989). 

Chemical contaminants from indoor sources:
Most indoor air pollution comes from sources inside the building. For example, adhesives, carpeting, upholstery, manufactured wood products, copy machines, pesticides, and cleaning agents may emit volatile organic compounds (VOCs), including formaldehyde. Environmental tobacco smoke contributes high levels of VOCs, other toxic compounds, and respirable particulate matter. Research shows that some VOCs can cause chronic and acute health effects at high 
concentrations, and some are known carcinogens. Low to moderate levels of multiple VOCs may also produce acute reactions. Combustion products such as carbon monoxide, nitrogen dioxide, as well as respirable particles, can come from unvented kerosene and gas space heaters, woodstoves, fireplaces and gas stoves. 

Chemical contaminants from outdoor sources:
The outdoor air that enters a building can be a source of indoor air pollution. For example, pollutants from motor vehicle exhausts; plumbing vents, and building exhausts (e.g., bathrooms and kitchens) can enter the building through poorly located air intake vents, windows, and other openings. In addition, combustion products can enter a building from a nearby garage. 

Biological contaminants: 
Bacteria, molds, pollen, and viruses are types of biological contaminants. These contaminants may breed in stagnant water that has accumulated in ducts, humidifiers and drain pans, or where water has collected on ceiling tiles, carpeting, or insulation. Sometimes insects or bird droppings can be a source of biological contaminants. Physical symptoms related to biological contamination include cough, chest tightness, fever, chills, muscle aches, and allergic responses such as mucous membrane irritation and upper respiratory congestion. One indoor bacterium, Legionella, has caused both 
Legionnaire's Disease and Pontiac Fever. These elements may act in combination, and may supplement other complaints such as inadequate temperature, humidity, or lighting. Even after a building investigation, however, the specific causes 
of the complaints may remain unknown. 

A Word About Radon and Asbestos... 
SBS and BRI are associated with acute or immediate health problems; radon and asbestos cause long-term diseases which occur years after exposure, and are therefore not considered to be among the causes of sick buildings. This is not to 
say that the latter are not serious health risks; both should be included in any comprehensive evaluation of a building's IAQ.  

Building Investigation Procedures:
The goal of a building investigation is to identify and solve indoor air quality complaints in a way that prevents them from recurring and which avoids the creation of other problems. To achieve this goal, it is necessary for the investigator(s) to discover whether a complaint is actually related to indoor air quality, identify the cause of the complaint, and determine the most appropriate corrective actions. An indoor air quality investigation procedure is best characterized as a cycle of information gathering, hypothesis formation, and hypothesis testing. It generally begins with a walkthrough 
inspection of the problem area to provide information about the four basic factors that influence indoor air quality: 
• the occupants  
• the HVAC system  
• possible pollutant pathways  
• possible contaminant sources.  

Preparation for a walkthrough should include documenting easily obtainable information about the history of the building and of the complaints; identifying known HVAC zones and complaint areas; notifying occupants of the upcoming investigation; and, identifying key individuals needed for information and access. The walkthrough itself entails visual inspection of critical building areas and consultation with occupants and staff. The initial walkthrough should allow the investigator to develop some possible explanations for the complaint. At this point, the investigator may 
have sufficient information to formulate a hypothesis, test the hypothesis, and see if the problem is solved. If it is, steps should be taken to ensure that it does not recur. However, if insufficient information is obtained from the walk through to construct a hypothesis, or if initial tests fail to reveal the problem, the investigator should move on to collect additional information to allow formulation of additional hypotheses. The process of formulating hypotheses, testing them, and 
evaluating them continues until the problem is solved. Although air sampling for contaminants might 
seem to be the logical response to occupant complaints, it seldom provides information about possible causes. While certain basic measurements, e.g., temperature, relative humidity, CO2, and air movement, can provide a useful "snapshot" of current building conditions, sampling for specific pollutant concentrations is often not required to solve the problem and can even be misleading. Contaminant concentration levels rarely exceed existing standards and guidelines even when occupants continue to report health complaints. Air sampling should not be undertaken until considerable information on the factors listed above has been collected, and any sampling strategy should be based on a comprehensive understanding of how the building operates and the nature of the complaints. 

Solutions to Sick Building Syndrome 
Solutions to sick building syndrome usually include combinations of the following: Pollutant source removal or modification is an effective approach to resolving an IAQ problem when sources are known and control is feasible. Examples include routine maintenance of HVAC systems, e.g., periodic cleaning or replacement of filters; replacement of water-stained ceiling tile and carpeting; institution of smoking restrictions; venting contaminant source emissions to the outdoors; storage and use of paints, adhesives, solvents, and pesticides in well ventilated areas, and use of these pollutant sources during periods of non-occupancy; and allowing time for building materials in new or remodeled areas to off-gas pollutants before occupancy. Several of these options may be exercised at one time. Increasing ventilation rates and air distribution often can be a cost effective means of reducing indoor pollutant levels. HVAC systems should be 
designed, at a minimum, to meet ventilation standards in local building codes; however, many systems are not operated or maintained to ensure that these design ventilation rates are provided. In many buildings, IAQ can be improved by operating the HVAC system to at least its design standard, and to ASHRAE Standard 62-1989 if possible. 
When there are strong pollutant sources, local exhaust ventilation may be appropriate to exhaust contaminated air directly from the building. Local exhaust ventilation is particularly recommended to remove pollutants that accumulate in specific areas such as rest rooms, copy rooms, and printing facilities. (For a more detailed discussion of ventilation, read Indoor Air Facts No. 3R, Ventilation and Air Quality in Office Buildings.) Air cleaning can be a useful adjunct to source 
control and ventilation but has certain limitations. Particle control devices such as the typical furnace filter are inexpensive but do not effectively capture small particles; high performance air filters capture the smaller, respirable particles but are relatively expensive to install and operate. Mechanical filters do not remove gaseous pollutants. Some specific gaseous pollutants may be removed by adsorbent beds, but these devices can be expensive and require frequent replacement of the adsorbent material. In sum, air cleaners can be useful, but have limited application. Education and communication are important elements in both remedial and preventive indoor air quality management programs. When building occupants, management, and maintenance personnel fully communicate and understand the causes and consequences of IAQ problems, they can work more effectively together to prevent problems from occurring, or to solve them if they do.  Additional Information For more information on topics discussed in this Fact Sheet, contact your state or local health department, a non-profit agency such as your local American Lung Association, or the following: 

National Institute for Occupational Safety and Health www.cdc.gov/niosh/homepage.html  
US Department of Health and Human Services 
4676 Columbia Parkway (Mail Drop R2) 
Cincinnati, Ohio 45226 
Public Relations Office  
American Society of Heating, Refrigerating and AirConditioning Engineers (ASHRAE) 
www.ashrae.org/  
1791 Tullie Circle, NE,  
Atlanta, Georgia 30329 
Building Owners and Managers Association 
International 
www.boma.org/  
1250 Eye Street, NW,  
Washington, DC 20005
Sick Building Group, LLC
3046 Wren Cir NW Kennesaw, GA 30144 US
Phone: 404-808-7239 Website: http://www.sickbuildinggroup.com/

Fibromyalgia Fibromyositis; Fibrositis Last reviewed: February 14, 2011. Fibromyalgia is a common syndrome in which a person has long-term, body-wide pain and tenderness in the joints, muscles, tendons, and other soft tissues. Fibromyalgia has also been linked to fatigue, sleep problems, headaches, depression, and anxiety. Causes, incidence, and risk factors The cause is unknown. Possible causes or triggers of fibromyalgia include: Physical or emotional trauma Abnormal pain response - areas in the brain that are responsible for pain may react differently in fibromyalgia patients Sleep disturbances Infection, such as a virus, although none has been identified Fibromyalgia is most common among women aged 20 to 50. The following conditions may be seen with fibromyalgia or mimic its symptoms: Chronic neck or back pain Chronic fatigue syndrome Depression Hypothyroidism (underactive thyroid) Lyme disease Sleep disorders Symptoms Pain in the main symptom of fibromyalgia. It may be mild to severe. Painful areas are called tender points. Tender points are found in the soft tissue on the back of the neck, shoulders, chest, lower back, hips, shins, elbows, and knees. The pain then spreads out from these areas. The pain may feel like a deep ache, or a shooting, burning pain. The joints are not affected, although the pain may feel like it is coming from the joints. People with fibromyalgia tend to wake up with body aches and stiffness. For some patients, pain improves during the day and gets worse at night. Some patients have pain all day long. Pain may get worse with activity, cold or damp weather, anxiety, and stress. Fatigue, depressed mood, and sleep problems are seen in almost all patients with fibromyalgia. Many say that they can't get to sleep or stay asleep, and they feel tired when they wake up. Other symptoms of fibromyalgia may include: Irritable bowel syndrome (IBS) Memory and concentration problems Numbness and tingling in hands and feet Palpitations Reduced ability to exercise Tension or migraine headaches Signs and tests To be diagnosed with fibromyalgia, you must have had at least 3 months of widespread pain, and pain and tenderness in at least 11 of 18 areas, including Arms (elbows) Buttocks Chest Knees Lower back Neck Rib cage Shoulders Thighs Blood and urine tests are usually normal. However, tests may be done to rule out other conditions that may have similar symptoms. Treatment The goal of treatment is to help relieve pain and other symptoms, and to help a person cope with the symptoms. The first type of treatment may involve: Physical therapy Exercise and fitness program Stress-relief methods, including light massage and relaxation techniques If these treatments do not work, your doctor may prescribe an antidepressant or muscle relaxant. The goal of medication is to improve sleep and pain tolerance. Medicine should be used along with exercise and behavior therapy. Duloxetine (Cymbalta), pregabalin (Lyrica), and milnacipran (Savella) are medications that are approved specifically for treating fibromyalgia. However, many other drugs are also used to treat the condition, including: Anti-seizure drugs Other antidepressants Muscle relaxants Pain relievers Sleeping aids Cognitive-behavioral therapy is an important part of treatment. This therapy helps you learn how to: Deal with negative thoughts Keep a diary of pain and symptoms Recognize what makes your symptoms worse Seek out enjoyable activities Set limits Support groups may also be helpful. Other recommendations include: Eat a well-balanced diet Avoid caffeine Practice good sleep routines to improve quality of sleep (See: Sleeping difficulty) Acupressure and acunpuncture Severe cases of fibromyalgia may require a referral to a pain clinic. Expectations (prognosis) Fibromyalgia is a long-term disorder. Sometimes, the symptoms improve. Other times, the pain may get worse and continue for months or years. Calling your health care provider Call your health-care provider if you have symptoms of fibromyalgia. Prevention There is no known prevention. References Abeles M, Solitar BM, Pillinger MH, Abeles AM. Update on fibromyalgia therapy. Am J Med. 2008;121:555-561. Häuser W, Bernardy K, Üceyler N, Sommer C. Treatment of fibromyalgia syndrome with antidepressants. JAMA. 2009;301:198-209. Wolfe F, Rasker JJ. Fibromyalgia. In: Firestein GS, Budd RC, Harris ED Jr., et al., eds. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 38. Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res. 2010;62(5):600-610. Review Date: 2/14/2011. Reviewed by: Michael E. Makover, MD is a professor and attending in rheumatology at the New York University Medical Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Website Builder